CUSTOM PROTEIN SERVICES

Making the unmakeable

Expressing your difficult protein at scale.

We genetically engineer fruit flies to express high-quality, recombinant proteins. Our custom protein production service is designed to address your challenges of producing difficult‐to‐express proteins while offering a flexible, scalable, and cost‐effective solution.

Up to 305 g/L*

200+ cell types

86% less GHGs

75% less water usage

*CHO equivalent titre. This is based on cost-ratio conversions of our typical EntoEngine titres to CHO titres.

Person wearing a black glove holding a vial of lyophilized protein

COST EFFICIENCY

FLEXIBLE BATCH SIZES

ON-DEMAND MANUFACTURING

SOLUBLE PROTEINS

WHAT YOU PAY FOR

  • DNA synthesis and injection
  • Balanced fly strains that stably express your protein
  • Western blot analysis
  • Protein purification
  • Genomic DNA PCR analysis
  • Process development
  • SDS-PAGE gel densitometry
  • Functionality validation by SPR (Surface Plasmon Resonance)
  • Optional advanced assays per request

WHAT TO EXPECT WITH US

We follow a risk-sharing milestone model.

Milestone 1: Successful generation of strains expressing protein of interest.

Milestone 2: Stable fly strain scale-up for continuous process development.

Milestone 3: Process development and production for validation and titre determination.

Milestones 4+: Additional QC and scale-up runs for large scale validation and production

WHAT WE EXPRESSED

Case Study:

Resolving Insolubility + Host Cell Toxicity

Case Study:

A Look Into Glycosylation

Case Study:

Expressing Homodimers

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